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1

Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

Maeki, Masatoshi, Kimura, Niko, Sato, Yusuke, Harashima, Hideyoshi, Tokeshi, Manabu

Journal:

Advanced Drug Delivery Reviews

Year:

2018

Language:

english

File:

PDF, 15.69 MB

english, 2018

2

Micro/Nano Devices for Chemical Analysis

Tokeshi, Manabu, Sato, Kiichi

Journal:

Year:

2016

Language:

english

File:

PDF, 154 KB

english, 2016

3

Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo

Sato, Yusuke, Hashiba, Kazuki, Sasaki, Kosuke, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 446 KB

english, 2019

4

Continuous-Flow Chemical Processing on a Microchip by Combining Microunit Operations and a Multiphase Flow Network

Tokeshi, Manabu, Minagawa, Tomoko, Uchiyama, Kenji, Hibara, Akihide, Sato, Kiichi, Hisamoto, Hideaki, Kitamori, Takehiko

Journal:

Analytical Chemistry

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

5

Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10 nm for Drug Delivery

Kimura, Niko, Maeki, Masatoshi, Sato, Yusuke, Note, Yusuke, Ishida, Akihiko, Tani, Hirofumi, Harashima, Hideyoshi, Tokeshi, Manabu

Journal:

Year:

2018

Language:

english

File:

PDF, 3.39 MB

english, 2018

6

Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery

Kimura, Niko, Maeki, Masatoshi, Sato, Yusuke, Ishida, Akihiko, Tani, Hirofumi, Harashima, Hideyoshi, Tokeshi, Manabu

Journal:

ACS Applied Materials & Interfaces

Year:

2020

File:

PDF, 4.55 MB

2020

7

Microchip-based immunoassay system with branching multichannels for simultaneous determination of interferon-γ

Kiichi Sato, Maho Yamanaka, Hiroko Takahashi, Manabu Tokeshi, Hiroko Kimura, Takehiko Kitamori

Journal:

ELECTROPHORESIS

Year:

2002

Language:

english

File:

PDF, 961 KB

english, 2002

8

Chemical processing on microchips for analysis, synthesis, and bioassay

Manabu Tokeshi, Yoshikuni Kikutani, Akihide Hibara, Kiichi Sato, Hideaki Hisamoto, Takehiko Kitamori

Journal:

ELECTROPHORESIS

Year:

2003

Language:

english

File:

PDF, 467 KB

english, 2003

9

An interface chip connection between capillary electrophoresis and thermal lens microscope

Kenji Uchiyama, Akihide Hibara, Kiichi Sato, Hideaki Hisamoto, Manabu Tokeshi, Takehiko Kitamori

Journal:

ELECTROPHORESIS

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

10

Monitoring of intercellular messengers released from neuron networks cultured in a microchip

Kiichi Sato, Akiko Egami, Tamao Odake, Manabu Tokeshi, Makoto Aihara, Takehiko Kitamori

Journal:

Journal of Chromatography A

Year:

2006

Language:

english

File:

PDF, 827 KB

english, 2006

11

Estimating the geostrophic velocity obtained by HF radar observations in the upstream area of the Kuroshio

Ryoko Tokeshi, Kaoru Ichikawa, Satoshi Fujii, Kenji Sato, Shoichiro Kojima

Journal:

Journal of Oceanography

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

12

Microchip-based chemical and biochemical analysis systems

Kiichi Sato, Akihide Hibara, Manabu Tokeshi, Hideaki Hisamoto, Takehiko Kitamori

Journal:

Advanced Drug Delivery Reviews

Year:

2003

Language:

english

File:

PDF, 1.33 MB

english, 2003

13

Single-Cell Analysis by a Scanning Thermal Lens Microscope with a Microchip: Direct Monitoring of Cytochrome c Distribution during Apoptosis Process

Tamaki, Eiichiro, Sato, Kiichi, Tokeshi, Manabu, Sato, Kae, Aihara, Makoto, Kitamori, Takehiko

Journal:

Analytical Chemistry

Year:

2002

Language:

english

File:

PDF, 177 KB

english, 2002

14

Surface current variability east of Okinawa Island obtained from remotely sensed and in situ observational data

Hisaki, Yukiharu, Tokeshi, Tsutomu, Fujiie, Wataru, Sato, Kenji, Fujii, Satoshi

Journal:

Journal of Geophysical Research

Year:

2001

Language:

english

File:

PDF, 1.52 MB

english, 2001

15

Integration of an Immunosorbent Assay System: Analysis of Secretory Human Immunoglobulin A on Polystyrene Beads in a Microchip

Sato, Kiichi, Tokeshi, Manabu, Odake, Tamao, Kimura, Hiroko, Ooi, Takeshi, Nakao, Masayuki, Kitamori, Takehiko

Journal:

Analytical Chemistry

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

16

Development of a Microchip-Based Bioassay System Using Cultured Cells

Goto, Makiko, Sato, Kiichi, Murakami, Atsushi, Tokeshi, Manabu, Kitamori, Takehiko

Journal:

Analytical Chemistry

Year:

2005

Language:

english

File:

PDF, 700 KB

english, 2005

17

Peer Reviewed: Thermal Lens Microscopy and Microchip Chemistry

Kitamori, Takehita, Tokeshi, Manabu, Hibara, Akihide, Sato, Kiichi

Journal:

Analytical Chemistry

Year:

2004

Language:

english

File:

PDF, 372 KB

english, 2004

18

Microchip-based enzyme-linked immunosorbent assay (microELISA) system with thermal lens detection

Sato, Kiichi, Yamanaka, Maho, Hagino, Tomokazu, Tokeshi, Manabu, Kimura, Hiroko, Kitamori, Takehiko

Journal:

Year:

2004

Language:

english

File:

PDF, 378 KB

english, 2004

19

Determination of Carcinoembryonic Antigen in Human Sera by Integrated Bead-Bed Immunoasay in a Microchip for Cancer Diagnosis

Sato, Kiichi, Tokeshi, Manabu, Kimura, Hiroko, Kitamori, Takehiko

Journal:

Analytical Chemistry

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

20

A micro-ELISA system for the rapid and sensitive measurement of total and specific immunoglobulin E and clinical application to allergy diagnosis

Ohashi, Toshinori, Mawatari, Kazuma, Sato, Kae, Tokeshi, Manabu, Kitamori, Takehiko

Journal:

Year:

2009

Language:

english

File:

PDF, 272 KB

english, 2009

21

[Japan Soc. Appl. Phys Digest of Papers. Microprocesses and Nanotechnology 2001. 2001 International Microprocesses and Nanotechnology Conference - Shimane, Japan (31 Oct.-2 Nov. 2001)] Digest of Papers. Microprocesses and Nanotechnology 2001. 2001 International Microprocesses and Nanotechnology Conference (IEEE Cat. No.01EX468) - DNA melting analysis on a microchip after PCR amplification

Slyadnev, M.N., Sato, K., Tokeshi, M., Kitamori, T.

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

22

[Japan Soc. Appl. Phys Digest of Papers. Microprocesses and Nanotechnology 2001. 2001 International Microprocesses and Nanotechnology Conference - Shimane, Japan (31 Oct.-2 Nov. 2001)] Digest of Papers. Microprocesses and Nanotechnology 2001. 2001 International Microprocesses and Nanotechnology Conference (IEEE Cat. No.01EX468) - Development of high performance immunoassay system using multichannel microchip

Yamanaka, M., Sato, K., Tokeshi, M., Katou, H., Kimura, H., Kitamori, T.

Year:

2001

Language:

english

File:

PDF, 182 KB

english, 2001

23

Kuroshio variations in the upstream region as seen by HF radar and satellite altimetry data

Ichikawa, K., Tokeshi, R., Kashima, M., Sato, K., Matsuoka, T., Kojima, S., Fujii, S.

Journal:

International Journal of Remote Sensing

Year:

2008

Language:

english

File:

PDF, 496 KB

english, 2008

24

A strategy for synthesis of lipid nanoparticles using microfluidic devices with a mixer structure

Maeki, Masatoshi, Saito, Tatsuyoshi, Sato, Yusuke, Yasui, Takao, Kaji, Noritada, Ishida, Akihiko, Tani, Hirofumi, Baba, Yoshinobu, Harashima, Hideyoshi, Tokeshi, Manabu

Journal:

Year:

2015

Language:

english

File:

PDF, 6.05 MB

english, 2015

25

Integrated chemical systems on microchips for analysis and assay. Potential future, mobile high-performance detection system for chemical weapons

Kikutani, Yoshikuni, Tokeshi, M., Sato, K., Kitamori, Takehiko

Journal:

Pure & Applied Chemistry

Year:

2002

Language:

english

File:

PDF, 532 KB

english, 2002

26

A microfluidic cell culture system for monitoring of sequential changes in endothelial cells after heat stress

Tazawa, Hidekatsu, Sato, Kenjiro, Tsutiya, Atsuhiro, Tokeshi, Manabu, Ohtani-Kaneko, Ritsuko

Journal:

Thrombosis Research

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

27

Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery

Sato, Yusuke, Note, Yusuke, Maeki, Masatoshi, Kaji, Noritada, Baba, Yoshinobu, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Journal of Controlled Release

Year:

2016

Language:

english

File:

PDF, 955 KB

english, 2016

28

SPIE Proceedings [SPIE BiOS 2000 The International Symposium on Biomedical Optics - San Jose, CA (Saturday 22 January 2000)] Scanning and Force Microscopies for Biomedical Applications II - Subsingle-molecule determination of nonfluorescent species by scanning thermal lens microscope and its application to single-cell measurement

Kitamori, Takehiko, Uchida, Marika, Egami, Akiko, Sekiguchi, Kazuya, Zheng, Jinjian, Sawada, Tsuguo, Tokeshi, Manabu, Sato, Kiichi, Kimura, Hiroko, Nie, Shuming, Tamiya, Eiichi, Yeung, Edward S.

Year:

2000

Language:

english

File:

PDF, 308 KB

english, 2000

29

Assessment of hepatic fibrosis with superb microvascular imaging in hepatitis C virus-associated chronic liver diseases

Koyama, Nobuko, Hata, Jiro, Sato, Tokeshi, Tomiyama, Yasuyuki, Hino, Keisuke

Journal:

Hepatology Research

Year:

2016

Language:

english

File:

PDF, 455 KB

english, 2016

30

Sub-Zeptomole Detection in a Microfabricated Glass Channel by Thermal-Lens Microscopy.

SATO, Kiyoshi, KAWANISHI, Hiroaki, TOKESHI, Manabu, KITAMORI, Takehiko, SAWADA, Tsuguo

Journal:

Analytical Sciences

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

31

Integration of Flow Injection Analysis and Zeptomole-Level Detection of the Fe(II)-o-Phenanthroline Complex.

SATO, Kiyoshi, TOKESHI, Manabu, KITAMORI, Takehiko, SAWADA, Tsuguo

Journal:

Analytical Sciences

Year:

1999

Language:

english

File:

PDF, 52 KB

english, 1999

32

Molecular Transport between Two Phases in a Microchannel.

SATO, Kiyoshi, TOKESHI, Manabu, SAWADA, Tsuguo, KITAMORI, Takehiko

Journal:

Analytical Sciences

Year:

2000

Language:

english

File:

PDF, 30 KB

english, 2000

33

Acceleration of an Enzymatic Reaction in a Microchip.

TANAKA, Yuki, SLYADNEV, Maxim N., SATO, Kiichi, TOKESHI, Manabu, KIM, Haeng-Boo, KITAMORI, Takehiko

Journal:

Analytical Sciences

Year:

2001

Language:

english

File:

PDF, 44 KB

english, 2001

34

Integration of Chemical and Biochemical Analysis Systems into a Glass Microchip.

SATO, Kiichi, HIBARA, Akihide, TOKESHI, Manabu, HISAMOTO, Hideaki, KITAMORI, Takehiko

Journal:

Analytical Sciences

Year:

2003

Language:

english

File:

PDF, 397 KB

english, 2003

35

Parallel Real-Time PCR on a Chip for Genetic Tug-of-War (gTOW) Method

NAITO, Toyohiro, YATSUHASHI, Ai, KAJI, Noritada, ANDO, Taeko, SATO, Kazuo, MORIYA, Hisao, KITANO, Hiroaki, YASUI, Takao, TOKESHI, Manabu, BABA, Yoshinobu

Journal:

Analytical Sciences

Year:

2013

Language:

english

File:

PDF, 689 KB

english, 2013

36

Highly Sensitive Detection of Non-Labeled Peptides Using UV Excitation Thermal Lens Microscope/Liquid Chromatography

HIKI, Shinichiro, TOKESHI, Manabu, KAKUTA, Masaya, MAWATARI, Kazuma, KIKUTANI, Yoshikuni, SATO, Kiichi, HIBARA, Akihide, SHIMURA, Kiyohito, UCHIDA, Naoyuki, KITAMORI, Takehiko

Journal:

Year:

2007

File:

PDF, 465 KB

2007

37

Investigation on Combustion in Diesel Engines using a Constant Volume Combustion Chamber : Effect of initial Temperature

FUJIMOTO, Hajime, SHIMADA, Toshio, SATO, Tokeshi

Journal:

Bulletin of JSME

Year:

1979

File:

PDF, 940 KB

1979

38

394PDevelopment of the immuno-wall device for rapid detection of ALK and ROS1 fusions in lung cancer

Yogo, N, Hase, T, Kasama, T, Hatta, T, OZAWA, N, Sato, M, Kaji, N, Tokeshi, M, Baba, Y, Hasegawa, Y

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 69 KB

english, 2018

39

The Use of a Microfluidic Device to Encapsulate a Poorly Water-Soluble Drug CoQ10 in Lipid Nanoparticles and an Attempt to Regulate Intracellular Trafficking to Reach Mitochondria

Hibino, Mitsue, Yamada, Yuma, Fujishita, Naoki, Sato, Yusuke, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

File:

PDF, 1.79 MB

2019

40

Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles

Sato, Yusuke, Okabe, Nana, Note, Yusuke, Hashiba, Kazuki, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Acta Biomaterialia

Year:

2019

Language:

english

File:

PDF, 1.33 MB

english, 2019

41

The effect of size and charge of lipid nanoparticles prepared by microfluidic mixing on their lymph node transitivity and distribution

Nakamura, Takashi, Kawai, Minori, Sato, Yusuke, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Molecular Pharmaceutics

Year:

2020

Language:

english

File:

PDF, 2.04 MB

english, 2020

42

The use of design of experiments with multiple responses to determine optimal formulations for in vivo hepatic mRNA delivery

Hashiba, Akari, Toyooka, Manaya, Sato, Yusuke, Maeki, Masatoshi, Tokeshi, Manabu, Harashima, Hideyoshi

Journal:

Journal of Controlled Release

Year:

2020

File:

PDF, 2.49 MB

2020

43

Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol)

Wang, Yubo, Quinsaat, Jose Enrico Q., Ono, Tomoko, Maeki, Masatoshi, Tokeshi, Manabu, Isono, Takuya, Tajima, Kenji, Satoh, Toshifumi, Sato, Shin-ichiro, Miura, Yutaka, Yamamoto, Takuya

Journal:

Nature Communications

Year:

2020

File:

PDF, 1.67 MB

2020

44

Rapid, Sensitive Universal Paper-Based Device Enhances Competitive Immunoassays of Small Molecules

Komatsu, Takeshi, Sato, Yuki, Maeki, Masatoshi, Ishida, Akihiko, Tani, Hirofumi, Tokeshi, Manabu

Journal:

Analytica Chimica Acta

Year:

2020

File:

PDF, 558 KB

2020